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KMID : 0361920140440030113
Korean Journal of Orthodontics
2014 Volume.44 No. 3 p.113 ~ p.118
Effects of various toothpastes on remineralization of white spot lesions
Jo Su-Yeon

Chong Hyun-Jeong
Lee Eon-Hwa
Chang Na-Young
Chae Jong-Moon
Cho Jin-Hyoung
Kim Sang-Cheol
Kang Kyung-Hwa
Abstract
Objective: The purpose of this in vitro study was to examine the effects of fluoridated, casein phosphopeptide?amorphous calcium phosphate complex (CPP-ACP)-containing, and functionalized ¥â-tricalcium phosphate (fTCP)-containing toothpastes on remineralization of white spot lesions (WSLs) by using Quantitative light-induced fluorescence (QLF-D) BiluminatorTM 2.

Methods: Forty-eight premolars, extracted for orthodontic reasons from 12 patients, with artificially induced WSLs were randomly and equally assigned to four treatment groups: fluoride (1,000 ppm), CPP-ACP, fTCP (with sodium fluoride), and control (deionized water) groups. Specimens were treated twice daily for 2 weeks and stored in saliva solution (1:1 mixture of artificial and human stimulated saliva) otherwise. QLF-D BiluminatorTM 2 was used to measure changes in fluorescence, indicating alterations in the mineral contents of the WSLs, immediately before and after the 2 weeks of treatment.

Results: Fluorescence greatly increased in the fTCP and CPP-ACP groups compared with the fluoride and control groups, which did not show significant differences.

Conclusions: fTCP- and CPP-ACP-containing toothpastes seem to be more effective in reducing WSLs than 1,000-ppm fluoride-containing toothpastes.
KEYWORD
Remineralization, Tooth paste, Cariology, White spot lesions, Tri-calcium phosphate
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